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We hope this will spark more meaningful conversations between patients and health care providers and ultimately lead to better health outcomes. Clinical Trial Results This approval was based on results from the SURMOUNT-OSA phase 3 clinical trials, which evaluated Zepbound (10 mg or 15 mg) for the treatment of moderate-to-severe OSA in adults with obesity, with and without positive airway pressure (PAP) therapy over the course of a year

If retatrutide is stopped, appetite regulation and metabolic effects gradually return to baseline