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Next, an orthotopic K7M2 osteosarcoma model with an active immune system was established to investigate the tumor targeting and therapeutic effects of NP4 (Fig
1, 2 IGF-1R is primarily activated by its high-affinity ligands, IGF-1 and IGF-2, though it can also bind insulin with lower affinity
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Step-by-Step Analytical Setup: Column: C18, 250 mm 4.6 mm, 5 m particles
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