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The Mayo Clinic indicates high doses of vitamin B-12, such as those used to treat a deficiency, might cause: Headache Nausea and vomiting Diarrhea Fatigue or weakness Tingling sensation in hands and feet Healthline says: In very rare cases, some people can experience side effects caused by allergic reactions or sensitivity In addition to helping athletes build muscle, vitamin B12 plays a role in maintaining nervous system function and brain health
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At 50 mg to 200 mg per dose, the high injection volume requires intramuscular (IM) administration or splitting the dose across multiple subcutaneous sites
Repeat determinations of iron and folic acid may reveal a complicating illness that might inhibit the response of the marrow
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