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In contrast, short-acting formulations such as exenatide and the older-generation agent lixisenatide are now prescribed far less frequently, and several formulations have been withdrawn from the market in certain countries, largely due to limited clinical uptake, the availability of more effective long-acting alternatives, and commercial considerations rather than confirmed safety concerns

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For example, obese diabetics are a special case and should not be given the full mortality and morbidity benefit for the weight-loss indication in addition to the diabetes indication

Thymosin beta4 accelerates dermal wound healing and may offer therapeutic value in treating tissue injury. Philp et al., Journal of Investigative Dermatology Joint and Tendon Repair Because of its role in reducing fibrosis and scar formation , TB500 is commonly used for tendonitis , ligament strain , and joint overuse injuries

Conversely, evaporative dry eye is predominantly attributed to elevated evaporation of the tear film, sometimes linked to meibomian gland dysfunction [63, 64]