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doi: 10.1017/S0031182013001108, 48 TaylorM
Moreover, the high estrogen levels often seen in PCOS patients during controlled ovarian stimulation may prematurely induce PGF release by activating estrogen receptor pathways, leading to a shortened luteal phase and functional insufficiency (41, 42)
We treated the MOLP-8 myeloma cell line with increasing concentrations of the ERK5-CHAMP RNK06138 for 24 h and observed a dose-dependent decrease in ERK5 protein levels with a Dmax (maximum degradation) of 74% and DC 50 (half-maximal degradation concentration) of 111.7 nM
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