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This side effect was more noticeable in patients who received the GLP-1RA treatment off-label, as a weight-loss medication

Persistent vomiting, severe constipation, dizziness, or signs of dehydration deserve medical attention

Across the major clinical programmes, these events were generally most pronounced during dose escalation and were typically described as mild to moderate in severity

These conversations usually include reviewing differences between FDA-approved medications and compounded alternatives, understanding required monitoring, and confirming follow-up expectations

doi: 10.1146/annurev-nutr-071816-064732 159 LiXSObeidSKlingenbergRGencerBMachFRberLet al