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Along with the GLP-1 pathway, it activates the GIP receptor (which plays a role in insulin secretion and fat storage) and the Glucagon receptor (which promotes fat breakdown and increases energy use)

A direct comparison with semaglutide published in the New England Journal of Medicine confirmed what many researchers suspected

Primarily, Ozempic stimulates insulin secretion from the pancreas when blood glucose levels are elevated, whilst simultaneously suppressing the release of glucagon, a hormone that raises blood sugar

Formulation and Administration GLP-1 agonists are available in various formulations, including injectable and oral medications