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Obesity: They are used as an adjunct to a reduced-calorie diet and increased physical activity to help promote weight loss in adults with a body mass index (BMI) of 30 or higher, or in adults with a BMI of 27 or higher who have at least one weight-related comorbidity, such as high blood pressure, type 2 diabetes, or high cholesterol

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Although it was registered in a clinical trial under the name Bepecin in 2015, the study did not result in any approved uses for this substance

Dentate gyrus-CA3 glutamate release/NMDA transmission mediates behavioral despair and antidepressant-like responses to leptin

No study measured BPC-157 cerebrospinal fluid concentrations to confirm central nervous system penetration in any species