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The cornerstone of therapy has traditionally been through vitamin B12 replacement, which helps restore red blood cell production and improve neurological function

What remains unknown Despite encouraging data, genuine unknowns exist: Effects beyond 6-9 months of continuous use have not been formally studied in animals or humans

If these develop while taking supplements, they warrant medical assessment to rule out ongoing deficiency or other neurological conditions

Notably, newborn infants are at risk of severe toxicity (as discussed in Contraindications), but in adults and older children, the small benzyl alcohol dose is very well tolerated