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This depends on their Vitamin B12 needs, how severe their deficiency is, and any other health issues
The real research sits in between, and the part that actually matters to your safety, the difference between the pill in a bottle and the needle in a clinic, usually gets buried under marketing copy
If you take very high doses of vitamin C, your body might absorb too much iron
Role of endothelial shear stress in the natural history of coronary atherosclerosis and vascular remodeling: molecular, cellular, and vascular behavior
Environmental and molecular mutagenesis , 58 (2), 6071
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