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It directly increases energy expenditure
Investigators considering KLOW use in the context of chronic kidney disease (CKD stage 3 or higher) should obtain baseline and serial monitoring of serum phosphate, calcium, creatinine, and parathyroid hormone, and consult a nephrologist before initiating dosing
Phase 2 trials demonstrated 24.2% average weight loss at 48 weeks, with the 12mg dose producing up to 27.3% reduction in some participants
In theory, if food moves more slowly, the colon has more time to absorb water, potentially firming up stools
Injectable compounded runs $99 to $249 a month and has the strongest evidence base
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