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Harsh cleansing compromises barrier function and increases sensitivity to active ingredients
Caffeine has the deepest evidence base, but prescription stimulants produce the largest cognitive effect, mostly in people with ADHD
Injecting too close to the belly button or other sensitive areas can also cause discomfort
Medication Adjustments If side effects remain problematic despite conservative measures, discuss with your physician options such as temporarily reducing the dose, extending time at current dose before escalating, or switching to the oral formulation which may have a different tolerability profile for some patients
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