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In case of skeletal muscle, however, mtDNA contents in GK rats were 50% decreased compared to the control at 12 and 24 week old, Similarly, OLETF and LETO control rats showed the age-dependent decrease of mtDNA content in liver and pancreas
Phase 2 weight loss (48 weeks): 22.8% at 8 mg maintenance 12 mg Weeks 13+ Maximum trial dose
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