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"Our findings provide a biological basis for investigating whether GLP-1-based medication may have direct effects in the joints -- beyond the known effects on weight and metabolism

Pancreatic DPP-4 As well as influencing glucose homeostasis through its more widespread systemic effects, as discussed above, there is some evidence to suggest that DPP-4 may have local actions in the endocrine pancreas

CVS Ventures Knownwell investment marks that inflection point: from selling prescriptions to rebuilding the healthcare infrastructure around them

This was the first weight loss medication to demonstrate a direct cardiovascular benefit independent of weight loss alone

Retatrutide represents the current frontier of what is pharmacologically possibleits weight loss numbers are, objectively, historic