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The second-line ADMs included GLP1-R agonists, sulfonylureas, dipeptidyl peptidase-4 (DPP-4) inhibitors, or sodium-glucose cotransporter 2 (SGLT2) inhibitors
It reflects the point at which oxidative degradation and peptide bond hydrolysis reduce the percentage of intact peptide below the threshold for reliable dosing
& Strata, F
I tell patients: give it 8 to 12 weeks, use a properly absorbed formulation, and keep expectations realistic." Dr
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