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All documentation and evaluation of this compound remain confined to investigational and non-clinical laboratory settings

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Modification of NAD-dependent isocitrate dehydrogenase by the 2',3'-dialdehyde [PMID: 3401017] Laboratory literature summary: Modification of NAD-dependent isocitrate dehydrogenase by the 2',3'-dialdehyde derivatives of NAD, NADH, NADP, and NADPH

That decline is one reason researchers started studying GHK-Cu in the first place

This gradual dose escalation minimises side effects such as nausea whilst allowing the body to adjust to the medication