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Defective glucose-dependent insulinotropic polypeptide receptor expression in diabetic fatty Zucker rats

There are no data on the presence of tirzepatide in breast milk, and data for use in pregnant patients are insufficient to determine risk

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This genetic insight helps explain why some patients feel full quickly while others need several weeks to experience appetite changes

These effects appear to result from the medications' impact on dopamine pathways and reward-seeking behavior ^10