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Heres why: Higher Disease Activity: Excess weight can increase inflammation throughout the body, potentially worsening psoriasis symptoms and joint pain in PsA

These effects are usually mild and go away quickly

The medication's local action in the gut means it has minimal systemic effects, which contributes to its generally favourable safety profile

Research has shown that GLP-1s effectively reduce blood glucose in people with type 2 diabetes

Much of the focus on the impact of GLP-1 receptor agonists (and combination drugs with components that target other receptors such as gastric inhibitory polypeptide collectively termed GLP-1s in this article) to date has been on their potential to improve long-term health outcomes for people with type 2 diabetes, obesity, and related cardiovascular diseases