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Description

This is the foundational cause of GLP-1 constipation

Coles 2007

When you lose 510% of body weight quickly, your body may take 48 weeks to recalibrate hormone signaling to your ovaries and uterus

Nature 364, 247249

A post-mortem study examining brain tissue from individuals with mood disorders found lower expression of GLP-1 receptors in the prefrontal cortex and hippocampus compared to healthy controls