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Clinical endocrinology of glucagon-like peptide-1

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Mean percent body weight change at 80 weeks, by dose: Retatrutide 4 mg : 19.0% (47.2 lbs) Retatrutide 9 mg : 25.9% (64.4 lbs) Retatrutide 12 mg : 28.3% (70.3 lbs) Placebo : 2.2% (5.5 lbs) Responder rates at the 12 mg dose are the more interesting number for clinicians

Mediators: weight loss at weeks 4, 12, 20, 28, 36, 44, 52, 62 and 72

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