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These results suggest that specific modification of peptide is equally significant to sequence optimization in terms of demonstration of a desired polypharmacology of a unimolecular dual or triple agonist

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3.4.2 HbA1c changes The analysis comparing HbA1c change between Tirzepatide and Semaglutide revealed a pooled effect size of 0.45 (95% CI: 0.88 to 0.02