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Anovulatory, premenopausal women with obesity and PCOS, without any severe chronic illness, provided us a homogeneous clinical population to control key variables known to affect taste perception, including sex, age, smoking, diabetes and other chronic conditions, as well as variability related to cyclical hormonal fluctuations, says Jane
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Since there are obvious differences between rodent and human physiology, it cannot be ignored that this may have a significant impact on the efficacy and safety of (any) novel agents
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