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If improvement plateaus or symptoms persist despite treatment, further investigation may be warranted to identify other contributing factors or alternative diagnoses
van Kleef, MD, PhD, and colleagues asked the next question, which is the more practical one
Researchers also found that diarrhea happened more often with tirzepatide than with some other diabetes medications
This framing supports the case for continued access to GLP-1 medications even after patients achieve their target weight, which relates to concerns about semaglutide withdrawal symptoms and weight regain after stopping treatment
Notably, researchers observed no similar reduction in hospitalizations unrelated to alcohol in T2D populations and smaller impacts on hospitalizations unrelated to alcohol in populations with obesity, suggesting the effect may be specific to alcohol-related outcomes, rather than confounding by underlying health status or general improvements in health
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