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An enzyme called DPP-4 (dipeptidyl peptidase-4) rapidly degrades it

Discontinuation rates due to adverse events were 12.2% and 18.2% with retatrutide 9 mg and 12 mg, respectively, compared to 4.0% with placebo

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A group size of six animals per arm was selected, consistent with commonly used cohort sizes in early-stage in vivo efficacy studies, and was sufficient to enable comparative survival analysis and evaluation of treatment-associated trends

AOD-9604 has been researched for various potential uses: It has been studied primarily as a weight loss medication that can be administered as an oral tablet [2]