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Thymosin beta-4 (often written as T4 or TB4) is a naturally occurring peptide, and TB-500 (or fequesetide) is a synthetic peptide based on a segment of TB4.3 4 While TB4 is made up of 43 amino acids, TB-500 contains only seven.4 5 Sometimes, especially in earlier research, you may see TB-500 referred to by its amino acid sequence, Ac-LKKTETQ.6 Insider Tip: The Ac- before amino acid sequences, like those of peptides, means its been permanently modified with an added acetyl group a process called N-terminal acetylation to protect it from degradation.7 8 This can improve a peptides stability,9 bioavailability,10 and other properties.11 Though nearly all synthetic peptides are protected in one way or another during synthesis, this protection is usually reversible
Each batch undergoes independent analytical testing to verify: Compound identity Assay accuracy Purity confirmation Microbial safety Endotoxin levels Heavy metal screening Full batch traceability All testing is performed by independent laboratories to ensure transparent verification and reproducible research material
The Compound That Healed Everything in Rats The team's first paper landed in 1992
1:1 Medical Support Science-backed guidance fda-approved Medical-Grade quality What are peptides
translation to another tissue, species, or route of exposure
