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By Lana Pine | Published on July 6, 2026 Fact checked by: Afton Woodward 4 min read GLP-1 receptor agonists like semaglutide and tirzepatide have helped millions of people lose significant weight and better manage blood sugar
Proposed Mechanisms DSIP appears to work through multiple pathways: it may affect GABA-A receptors, the same inhibitory pathways targeted by common sleep medications
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Thats because GLP-1 receptors are proteins found on cell surfaces throughout the body, meaning anywhere one appears, the medication can make a difference
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