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However it should be noted that according to Stanley [168], over the past 40 years, there have been only two clear examples of disorders directly due carnitine deficiency that have provided evidence of unequivocal benefit from carnitine treatment

Yu et al., 2017

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Over time, this impaired bile release can interfere with fat digestion and increase the likelihood of gallbladder dysfunction, particularly during rapid or prolonged medication-assisted weight loss