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Lyophilized vs liquid stability Extremely stable Water removed = minimal degradation 2-3 years shelf life (refrigerated) 3-5 years (frozen) Can survive room temp short periods Liquid (reconstituted) : Much less stable Degradation begins immediately 28 days max with bacteriostatic water 1-3 days with sterile water Must stay refrigerated This is why peptides ship as powder : Stability during shipping, longer shelf life, easier storage
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The GLP-1 analogs liraglutide and semaglutide reduce atherosclerosis in ApoE-/- and LDLr-/- mice by a mechanism that includes inflammatory pathways
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