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No hepatic impairment pharmacokinetic study exists for BPC-157 in humans

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Therefore, supplementation is needed

and people with conditions that cause nutrient malabsorption and/or gastrointestinal blood loss (such as celiac disease, ulcerative colitis, and Crohn's disease)

Where Selank and Semax have relatively defined signalling frameworks, DSIP is distinguished by an unresolved mechanism a difference researchers should weigh when selecting a compound for a given study design