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These plateaus usually resolve spontaneously within two to four weeks
At normal dietary levels (12 mcg), absorption relies on intrinsic factor and maxes out around 1.52 mcg per meal
Lang, A
[343] These dietary changes can potentially delay the onset and slow the progression of AMD, although supplementation does not prevent its development
These two characteristics make it inherently unsuitable for standard topical delivery: it degrades before it absorbs, and it repels the lipid-rich skin barrier
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