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Ozempic, Mounjaro, and Rybelsus are diabetes medications a provider may prescribe off-label because they can also cause weight loss, per the brand's own FAQ

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Needham D, Anyarambhatla G, Kong G, Dewhirst M

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If the fat content of the chyme is too high, cholecystokinin (CCK) is released, which stimulates contraction of the gall bladder so that bile salts (which emulsify the fats) are secreted into the duodenum, and also reduces gastric emptying

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Astrocyte-derived lactate is taken up by neurons and elevates histone H3 lysine 9 lactylation (H3K9la), which in turn facilitates lipid transport from neurons back to astrocytes

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Specifically, they investigated a class of drugs known as glucagon-like peptide-1 receptor agonists, or GLP-1RAs

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