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It is part of a broader movement toward treatments that focus on long-term skin function rather than quick fixes

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And its treatment requires an integrated approach that encompasses lifestyle and behavioral therapy, pharmacotherapy, as well as as Bariatric surgery when indicated

It is important to recognise that weight loss is rarely linearplateaus are common and do not necessarily indicate treatment failure

The ESI source parameters were manually optimized as follows: capillary voltage, 3.5 kV