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In this system, Atg4, Atg7, and Atg3 mediate the conjugation of soluble LC3 (microtubule-associated protein 1 light chain 3) to phosphatidylethanolamine (PE), producing LC3-II
We delineated the molecular cascade linking BPC157 engagement to upregulated proangiogenic factor expression, thereby establishing a comprehensive mechanistic framework for its therapeutic actions
This dual action promoting new vessel formation while simultaneously optimizing vascular tone distinguishes BPC-157 from other angiogenic compounds
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