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They found that piperazine erastin significantly decreased the size and number of tumor foci in the liver of DEN/CCl4-induced mice and the volume of Bel-7402 cell xenografts, accompanied by reduced levels of GPX4 expression
The brake is a hormone called somatostatin
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Building on this, exosome-based systems are emerging as a superior solution, capitalizing on their role as natural nanocarriers with low immunogenicity (Yuan et al., 2018
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