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Chung SW, Kim GC, Kweon S, Lee H, Choi JU, Mahmud F, et al
This is the rationale for using vasodilator drugs such as phosphodiesterase (PDE) III inhibitors, papaverine, and pentoxifylline or micronutrients like magnesium (Mg 2+ ) which seem to have protective effects in the noise-exposed cochlea (Figure 2)
For optimal absorption, consider administering injections in the evening and rotating injection sites to enhance comfort
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