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That volume of reviews tells a real story, one that is more nuanced than the headline rating of 3.9 out of 5 suggests
If side effects become intolerable despite optimisation strategies, dose reduction or treatment discontinuation may be necessary
We accounted for age, sex, BMI, smoking history, chronic steroid usage, and weight change over time
Initial side effects typically subside, but longer-term microbiome changes continue evolving
Rather than targeting a single pathway, researchers are studying how activating three hormone receptors together may influence several aspects of metabolic function
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