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Discordances in ER, PR and HER2 receptors after neoadjuvant chemotherapy in breast cancer
Introduction Over the past few years, theres been a tremendous interest in boosting NAD +
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These approaches provide spatially resolved information on tumour metabolic activity and acidosis, which reflect underlying cellular proliferation rates and microenvironmental stress
187,188 Deciphering the context-specific regulation and plasticity of DDR, as well as its interplay with oncogenic signaling and tumor evolution, is critical for the development of rational therapeutic interventions (Fig
