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Similar content being viewed by others Subjects Introduction Obesity is a chronic disease characterised by excess adiposity that impairs health and affects about 650 million people worldwide [1, 2]

Focus on nutrition

Exercise and diet were just not making a difference, especially now that my entire life was different too, with little sleep, an ever-changing meal schedule (which often meant I was eating the crusts left behind from my kids peanut butter and jelly sandwiches), and stress, all the stress

44, 77 Methymalonic acid, a metabolite of PPA, results in abnormal mitochondrial morphology, 78 tissue specific ETC dysfunction, 79 inhibition of the complex I and II function when interacting with complex III in the brain 80 and reductions in reduced glutathione, 78 similar to the patient cohort presented and the PPA animal model

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