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For diarrhoea , temporarily reduce high-fat and high-fibre foods, and focus on easily digestible options

2.4 Transition probabilities Consistent with previous obesity modeling studies (51)

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Individuals should be advised to contact their GP or diabetes specialist nurse promptly if they experience: Persistent vomiting or diarrhoea lasting more than 24 hours Inability to maintain adequate fluid intake Signs of dehydration : dizziness, reduced urine output, dark-coloured urine, dry mouth, or excessive thirst Unexplained fatigue or weakness Swelling of the ankles, feet, or face (which may indicate fluid retention or worsening kidney function) Patients with pre-existing kidney disease should be particularly vigilant and may benefit from more frequent contact with their healthcare team during treatment initiation

Nrregaard PK, Deryabina MA, Tofteng Shelton P, Fog JU, Daugaard JR, Eriksson PO, et al