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If you use sterile water, you should draw all doses into individual syringes immediately after reconstitution and store them separately

Eventually, this phenomenon became known as the Jarisch-Herxheimer reaction. Over the years, patient communities have adopted a shortened version of the full name, calling them Herxheimer reactions, which Ill use moving forward, or herxes. The reaction tends to happen in people with spirochetal infections, such as Lyme disease, relapsing fever, and others, when theyre treated with antibiotics, according to a medical review in StatPearls

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The initiation of this inflammatory process is complex and involves multiple factors