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In the Phase 2b VESPER-1 trial, dosing was given as 28 weekly doses to characterize dose-response, with the intent to transition to monthly dosing in Phase 3
This makes it straightforward to measure doses ranging from 0.5mg to 2mg or higher
This reduced synthetic capacity means older adults often start with deeper deficits and may need more sessions before experiencing the same benefits younger individuals notice sooner
Buprenorphine can be prescribed and dispensed by certified healthcare providers, often in sublingual tablet or film form, allowing for greater access to treatment
The good thing however is most of them are not of a permanent kind
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