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With regard to nicotine use disorder, a randomized trial evaluating dulaglutide for smoking cessation found that abstinence rates at 12 weeks did not differ significantly between the dulaglutide and placebo groups (Lengsfeld et al., 2023)

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42) In SUSTAIN-6, patients treated with semaglutide had a lower risk of developing or worsening nephropathy, but a higher risk of complications from diabetic retinopathy than those receiving placebo (40)

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This means that IF could be a technique to lose fat without losing lean body mass [21, 41]