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For example, general control nonderepressible 2 (GCN2) is activated by amino acid starvation, whereas protein kinase-like endoplasmic reticulum kinase (PERK) is activated by endoplasmic reticulum (ER) stress 15
The reducing environment promotes the DNA binding of HIF-1 in the nucleus, which is achieved by TXN-mediated Ref-1 reduction [28, 29]
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Mitochondrial copper homeostasis and its derailment in Wilson disease
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