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Missing by 4 or More Days If more than four days have passed since your scheduled injection, the guidance changes

Measurable weight loss typically appears by week 8 to 12, with the largest reductions occurring during the first 6 to 9 months as the dose is titrated up

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In other cases no clear changes are perceived, especially if there is no specific need or if the period of use is short

A complete medical history, including cardiovascular risk factors, thyroid disease, pancreatitis history, and current medications, is essential before considering GLP-1 agonist therapy