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This increase in visceral abdominal fat is linked with increased inflammation and free fatty acids that impair metabolic function, and is also linked to a higher risk of cardiovascular disease and metabolic syndrome
This increase in VAT metabolic activity correlates strongly with the degree of weight loss observed in patients
In this population, we confirmed that tirzepatide use significantly reduced hemoglobin A1c by 1.15% and produced a nearly 10% reduction in weight after a mean duration of 13.89 months compared to baseline
Role of IGF-1 in Tissue Repair and Regeneration. Endocrinology Reviews
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