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The message to the patient is that we are still investigating if these drugs put them at higher risk of ischemic optic nerve damage
It is a bit staining - green
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M1 glutamate then serves as a nitrogen donor to transfer the 15 N onto the branched-chain ketoacids in the reverse transaminase reaction to form M1 leucine, M1 isoleucine, or M1 valine (Supplemental Figure 6A)
The therapy is not dangerous
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