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Semaglutide is highly protein-bound and not expected to be dialyzable
Patients who combined GLP-1 medications with supervised exercise maintained significantly more weight loss one year after stopping treatment compared to those who relied on medication alone
GLP-1 receptor agonists cause lean mass loss because any significant calorie deficit triggers the body to break down both fat and lean tissue for energy
The study was observational and relatively small, but the findings were promising
Gomes FE, Weekes PW
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