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Sikiric P, Hahm KB, et al

Faster metabolism, sharper focus, and energy that lasts

A clinical case series reported that DSIP administration during opioid detoxification reduced withdrawal severity and improved sleep quality in patients undergoing tapering protocols (Iyer et al., Neurosci Biobehav Rev, 1988

Clinical Insight In a single-arm pilot study involving individuals with non-alcoholic fatty liver disease (NAFLD), 300 mg/day of oral glutathione for four months was associated with improvements in liver enzyme levels, blood lipids, and hepatic fat content (Honda et al., 2017)

Activation of the SIRT1 pathway appears to be a core therapeutic target for these effects of irisin