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[28] This raises the possibility that this extracellular glutamate plays an "endocrine-like" role as part of a larger homeostatic system
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in contrast, the genes involved in fatty acid oxidation, such as carnitine palmitoyl transferase 1 ( Cpt1 ) and fatty acid binding protein 1 ( Fabp1 ), Acyl-CoA oxidase ( Acox , the rate-limiting enzyme in peroxisomal -oxidation of fatty acids), and peroxisome proliferator-activated receptor- ( PPAR- ) (Figures 2J-M), the lipid exporting genes such as microparticle triglyceride transfer protein ( Mttp ) and apolipoprotein B ( Apob ) were decreased by feeding a MCD diet for 3 weeks (Figures 2N,O)