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Dietary Deficiency: If your deficiency was purely due to diet (e.g., a vegan not supplementing) and youve since adjusted your diet or started regular oral supplements, you might eventually be able to space out injections more or even switch to oral maintenance, though this should always be carefully managed by your GP
Overdose of certain B vitamins can cause symptoms such as gastrointestinal upset, skin lesions, or neurological abnormalities
What Is Vitamin B12 and Why Do You Need It
In turn, this may contribute to the development of depression by increasing oxidative stress, DNA damage, and cell death in the body ( A 2020 study with 132 children and teens, 89 with and 43 without depression, found that the participants with depression had lower B12 levels and higher levels of homocysteine compared with those without depression ( In addition to depressive symptoms, low or deficient B12 levels may lead to other mental conditions, including psychosis and mood disorders ( Because a deficiency in B12 negatively impacts the central nervous system, people with low or deficient B12 levels may feel foggy-headed and have difficulty concentrating and completing tasks ( Fortunately, studies show that mental impairment related to low B12 levels can improve with B12 treatment
B12 reduces circulating levels of homocysteine, a compound linked to increased risk of heart attack and stroke
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